Clinical and experimental vaccine research
Alopecia universalis following human papillomavirus vaccine administration: a case report.
Yinhua Wu, Xiaoyan Liu, Jianjun Qiao, Hong Fang
Published: 202510.7774/cevr.2025.14.e36
Abstract
Open AccessThe 9-valent human papillomavirus vaccine (9vHPV) protects against 9 HPV genotypes linked to cervical cancer and genital warts. While rare, HPV vaccines may trigger autoimmune reactions. Alopecia areata (AA) is a chronic autoimmune disease that causes non-scarring alopecia. Similarly, the development of AA induced by vaccines is a rare occurrence. This report presents a case of a healthy female who developed alopecia universalis after 9vHPV vaccination, aiming to document the event, share treatment, and highlight the need for prompt medical attention.