Post-COVID-19 Inflammatory Myopathy With Dermatomyositis-Mixed Connective Tissue Disease (MCTD) Overlap Features and Epiglottitis: A Case Report.
Nicholas Lorenz, Amia Mourad, Grant Weiderman, Juan Daniel Pulido
Abstract
Open AccessAutoimmune inflammatory myopathies can emerge after viral illnesses and may present with a wide range of neuromuscular and systemic symptoms. Post-viral immune dysregulation may unmask or trigger overlap syndromes characterized by muscle inflammation, dysphagia, airway involvement, and broader immune activation. This report describes a case of inflammatory myopathy with dermatomyositis and mixed connective tissue disease-associated antibodies occurring after a recent COVID-19 infection, highlighting the diagnostic challenges and severity of presentation. The case underscores the importance of recognizing post-COVID autoimmune complications and initiating timely immunosuppressive therapy to reduce long-term morbidity.