Journal of biomedical research
NS3 epitope-decorated nanoparticles produced in bacteria trigger potent T cell immunity against hepatitis C virus.
Victor V Kuprianov, Lyudmila I Nikolaeva, Maya D Stuchinskaya, Аnna A Zykova, Nikolai V Ravin
Published: 202510.7555/JBR.39.20250197
Abstract
The highly conserved human leukocyte antigen-A2 (HLA-A2)-restricted epitope NS3-1073 represents a promising candidate for a therapeutic vaccine against hepatitis C virus (HCV). In this study, we engineered a set of fusion proteins based on the artifi…
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