Annals of internal medicine
Efficacy and Safety of Bisphosphonates for Complex Regional Pain Syndrome : A Systematic Review and Meta-analysis.
Michael C Ferraro, Neil E O'Connell, Andreas Goebel, Ruaraidh Hill, Ffion Curtis, Jack Wilkinson, Jacqueline R Center, Sylvia M Gustin, Aidan G Cashin, James H McAuley
Published: 202510.7326/ANNALS-25-03693
Abstract
BACKGROUND: Clinical guidelines recommend bisphosphonates for complex regional pain syndrome (CRPS) despite limited evidence of efficacy. PURPOSE: To determine the efficacy and safety of bisphosphonates compared with placebo for CRPS. DATA SOURCES: M…
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