Syringe-assisted aspiration combined with mechanical aspiration thrombectomy effectively alleviates lower extremity deep vein thrombosis.

OBJECTIVE: To evaluate the safety and efficacy of syringe-assisted aspiration combined with mechanical aspiration thrombectomy in the management of lower-extremity deep vein thrombosis (DVT). METHODS: A retrospective analysis was conducted on 112 patients with DVT admitted to our hospital between January 2024 and June 2025. Patients were allocated to either the Mechanical Aspiration group (MA group, n = 50) or the Syringe-Assisted Mechanical Aspiration group (SMA group, n = 62). Outcomes compared between the two groups included stent implantation rate, thrombolysis duration and thrombolytic drug dosage, limb swelling rate, thrombus clearance rate, lower-limb circumference difference, venous patency score, Villalta scale for post-thrombotic syndrome, hemodynamic parameters, quality of life, complications, and recurrence. RESULTS: Baseline characteristics were comparable between the two groups. The SMA group demonstrated a lower stent implantation rate, shorter thrombolysis duration, higher limb deswelling and thrombus clearance rates, and lower urokinase dosage, hospitalization time, and medical costs (P < 0.05). All clinical indicators improved after treatment, with greater improvements observed in the SMA group. No significant differences were found in complication or recurrence rates between the groups (P > 0.05). CONCLUSION: Syringe-assisted aspiration combined with mechanical aspiration thrombectomy is an effective and safe treatment option for lower-extremity DVT. This combined approach can reduce thrombolytic drug requirements and hospitalization costs, enhance hemodynamics and quality of life, and demonstrate a favorable safety profile.