Plasma alterations in immunoglobulin G, immunoglobulin M, immunoglobulin A, serum transferrin, serum albumin, prealbumin, interleukin 6 and serum C-reactive protein after immune-type enteral nutrition support in patients undergoing radical resection of colon cancer.

Background: This study aims to evaluate the effects of high-quality nursing combined with immune-type enteral nutrition (IEN) support on postoperative recovery, nutritional status, immune function, inflammatory response, and complication rates in patients undergoing radical colon cancer resection. Methods: A total of 106 patients with colon cancer who underwent radical resection were randomly divided into a control group (CG) and an observation group (OG). The CG received routine nursing care and parenteral nutrition support, while the OG received high-quality nursing care and immune-type enteral nutrition support. Key outcomes were assessed, including recovery times, nutritional markers, immune function, inflammatory response, quality of life (QLQ-C30 scores), complication incidence, and nursing satisfaction. Results: The OG demonstrated significantly shorter recovery times for bowel sounds, exhaust gas, defecation, time to get out of bed, and overall hospital stay compared to the CG (P<0.05). The incidence of complications was also lower in the OG (3.77% vs. 16.98%, P=0.025). Nutritional markers such as serum transferrin (TFN), prealbumin (PA), and albumin (ALB) were significantly higher in the OG (P<0.05), along with increased levels of immunoglobulins (IgG, IgA, and IgM) and reduced inflammatory markers (CRP and IL-6, P<0.05). Quality of life scores and nursing satisfaction were significantly better in the OG (P<0.05). Conclusions: High-quality nursing combined with immune-type enteral nutrition support significantly enhances postoperative recovery, improves nutritional and immune status, reduces inflammation, lowers complication rates, and boosts the quality of life and nursing satisfaction in patients undergoing radical resection for colon cancer. This approach provides an effective strategy for promoting better outcomes in this patient population.