Evaluation of Chitosan (Axiostat®) as a Pulpotomy Agent in Primary Molars: An In Vivo Study.

Background: In primary teeth, pulpotomy is a well-established intervention for managing cariously exposed coronal pulp, with formocresol long considered the gold-standard medicament. Recent research focuses on wound-healing phenomena and the use of regenerative materials like chitosan owing to its functional versatility and unique characteristics. Aim: To assess the clinical and radiographic outcomes of using chitosan as a pulpotomy agent in primary molars. Materials and methods: Children aged 4-9 years, free from systemic illnesses and in need of pulpotomy, were selected. About 50 teeth were assigned to two groups: group I (chitosan) and group II (formocresol), and all treated teeth received stainless-steel crowns. Clinical and radiographic parameters were assessed at 1, 3, and 6 months posttreatment. The Chi-squared test was applied to compare the parameters and analyze the differences between the groups at the various time intervals. Results: Group I (chitosan) demonstrated a clinical and radiographic success rate of 95.6%, while group II (formocresol) achieved 100%. The variation between the groups was not statistically significant. Conclusion: The study indicated that chitosan (Axiostat®) can be considered a reliable pulpotomy agent in primary dentition and an effective substitute for formocresol. How to cite this article: Krishna N, Rai K, Manju R, et al. Evaluation of Chitosan (Axiostat®) as a Pulpotomy Agent in Primary Molars: An In Vivo Study. Int J Clin Pediatr Dent 2025;18(S-1):S61-S65.