Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnostiHumansProto-Oncogene Proteins B-rafMultiple MyelomaPrecision MedicineProtein Kinase Inhibitors
Precision medicine in hemato-oncology - treatment of refractory multiple myeloma with massive extramedullary involvement using BRAF/ MEK inhibitors.
M Štork, J Kotašková, E Ondroušková, M Borský, A Marečková, N Sendlerová, J Mayerová, M Brada, I Boichuk, K Menšíková, Z Adam, M Krejčí, V Sandecká, Z Jelínková, M Krtička
Published: 202510.48095/ccko2025390
Abstract
BACKGROUND: Multiple myeloma (MM) with extramedullary disease (EMD) represents a subgroup with particularly poor prognosis. The application of precision medicine principles, especially targeted therapy based on the tumor's molecular profile, is a pot…
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