Association between polycystic ovary syndrome and systemic immune inflammation index and other inflammation markers; a case-control study.

Aim: The aim of this study was,to determine the relationship between the systemic immune inflammation index-, which is a new inflammatory marker, and other inflammatory markers in patients with polycystic ovary syndrome. Methods: This case-control study was conducted by exaimining patients who presented at the Gynecology and Obstetrics Outpatient Clinic of Derince Training and Research Hospital between 2018-2022. Inflammatory markers were compared in hemogram parameters of 180 patients with polycystic ovary syndrome and 178 control group subjects. The two groups were compared in respect of hemoglobin(Hb), white blood cell (Wbc), platelet (Plt), neutrophil (Neu), lymphocyte (Ly), red cell distribution width(RDW), main platelet volume (MPV), platelet distribution width (PDW), neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) and systemic immune inflammation index (SII)values. Results: The hemoglobin, white blood cell, platelet, neutrophil, lymphocyte,neutrophil lymphocyte ratio,and systemic immune inflammation index values were determined to be statistically significantly higher in PCOS patients than in the control group. Conclusion: Elevated values of inflammatory markers can be detected in patients with polycystic ovary syndrome,- supporting the presence of inflammation.