Role of human umbilical cord mesenchymal stem cells in diabetic kidney disease.
Yan Liu, Xiao-Qian Shan, Yu-Jiao Li, Wei-Li Gao, Lan Zhao
Abstract
Open AccessOne of the most prevalent long-term effects of diabetes is diabetic kidney disease (DKD), which is linked to problems with the metabolism of amino acids, fats, and carbohydrates. The fundamental pathogenic mechanisms of DKD cannot be adequately treated by current clinical medicines; they can only slow the illness's progression to end-stage renal disease. We will concentrate on integrating human umbilical cord mesenchymal stem cell (hUC-MSC)-related mechanisms and potential applications into the therapy of DKD, as this work shows that hUC-MSCs can be used to treat metabolic liver obesity associated with diabetes. Future studies on the connection between hUC-MSCs and related illnesses ought to be promoted.