The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Depletion of BIS in astrocytes aggravates reactive gliosis following photothrombotic brain injury.
Soon-Young Jung, Ji-Won Hwang, Hye Hyeon Yun, Kyunghyun Yoo, Hong Lim Kim, Yuna Oh, Sung Won Jung, Joo Youn Kim, Sun-Nyoung Hwang, Seong Yun Kim, Seung-Hyun Jung, Mun-Yong Lee, Jeong-Hwa Lee, Tae-Ryong Riew
Published: 202610.4196/kjpp.25.361
Abstract
BIS (Bcl-2-interacting cell death suppressor, or BAG-3), is a multifunctional co-chaperone that maintains protein quality control via autophagy and proteostasis. Following the central nervous system (CNS) injury, BIS expression is markedly upregulate…
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