The Nigerian postgraduate medical journalHumansMendelian Randomization AnalysisOsteoarthritisGenome-Wide Association StudyMetabolic Networks and Pathways
Mendelian Randomisation Uncovers Causal Immune-Metabolic Networks in Osteoarthritis: Insights from Immune Cell and Metabolite Interactions.
Chuanliang Chen, Xiaochong Zou, Ke Zhang, Zeming Li, Xifan Zheng, Xiaorong Lu, Jun Yao
Published: 202510.4103/npmj.npmj_187_25
Abstract
BACKGROUND: The synergistic effect of immune dysfunction and metabolic disorder has gradually become a research focus in osteoarthritis (OA). AIMS: This study investigated the causal role of metabolites mediating immune cells in OA through a Mendelia…
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