Evaluation of Role and Efficacy of Autologous Platelet-Rich Plasma Injection Treatment for Hair Loss: A Prospective Clinical Trial.

Objective: The purpose of this study is to assess the efficacy and safety of autologous platelet-rich plasma injections in male and female patients with androgenetic alopecia. Method: A prospective clinical study on 5 patients with moderate to severe alopecia involving PRP preparation from patients' own blood using the double-spin method that was subsequently injected three times at 4-week intervals. Hair follicle assessment was performed based on the pull test, macroscopic camera pictures, biopsy, and patient surveys: during baseline and 3-week, 6-week, and 3-month follow-up visits. Results: After the third PRP injection, all patients displayed a considerable improvement in follicle density and a drop in hair loss. At six weeks, hair follicle density rose from baseline to 38.6 ± 7.6 at 3 months. Moreover, hair follicle thickness increased. In the satisfaction survey, scores improved with an average of 8.2 over a ten-week period. There were no major side consequences. Conclusion: Autologous PRP injection is a safe and effective procedure that significantly improves hair density and patient satisfaction.