Clinical and Epidemiological Profile of HIV TB Coinfection Among Adult Male and Female Population Across the City of Pune - A Cross-sectional Observational Study Protocol.

Background: HIV TB is a rising challenge in India which a few studies have explored this association in Indian population. Recent studies are missing to help form policies and understand socio demographical factors which affect the prevalence and influence the treatment outcome. Objective: This study assesses the sociodemographic and clinical profile of HIV TB co infection associated with the agent, host and environmental factors among HIV positive adults across the city of Pune, India. Materials and Methods: The study will be carried out in Pune city, across 5 ART centers among adult HIV positive patients. The sample size is 140 samples and convenience sampling will be used. All ethical norms will be duly followed. The data collection through a validated questionnaire will be related to gender/sexual orientation, socio economic status, education, occupation, life-style, height, weight, BMI, family and medical history, viral load, bacterial count, type of TB and duration of HIV, WHO staging of the disease. SPSS 24.0 IBM Analytics will be used for the analysis. Descriptive and inferential statistics will be carried out. Conclusion: The type of TB (pulmonary or extrapulmonary), WHO clinical staging of HIV, previous infection and associated medical history's effects on HIV TB coinfection will be explored.