Role of therapeutic plasma exchange in myasthenia gravis with thymoma: A case series.

Autoimmune myasthenia gravis (MG) is sometimes associated with thymic abnormalities. Thymectomy is performed in cases of MG with a thymoma or general MG that is resistant to medical therapy. The aims and objectives of the study are to assess the survivability and response to plasma exchange in patients planned for thymectomy in unstable disease activity status of MG. Plasma exchange is indicated before and after thymectomy in unstable disease activity status. Here, we are presenting case summary of five patients undergoing plasma exchange for unstable disease activity status. The outcome was poor in patients having Masoka staging III and Iva, respectively. The survival rate was 60% during an unstable state of MG with thymoma in our study.