Journal of gynecologic oncology
Molecular and pathological analysis of FOXL2 and TERT promoter mutations in adult-type granulosa cell tumors of the ovary: a study of 64 Japanese patients.
Satoshi Yanagida, Yuichi Shoburu, Takako Kiyokawa, Masami Iwamoto, Misato Saito, Eitaro Suzuki, Daito Noguchi, Ayako Kawabata, Ryusuke Kaya, Toshiyuki Seki, Chie Nagata, Motoaki Saito, Hirokuni Takano, Kyosuke Yamada, Masataka Takenaka
Published: 202510.3802/jgo.2026.37.e44
Abstract
OBJECTIVE: Adult-type granulosa cell tumors of the ovary (aGCTs) show ambiguous morphology and may be misdiagnosed as other tumors. Recently, heterozygous FOXL2 C402G mutations and TERT promoter C228T mutation have been reported as diagnostic and pro…
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