Journal of visualized experiments : JoVENeurofibromatosis 1HumansAnimalsSciatic NerveMice
An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas.
Manuela Ye, Aurélien Bore, Sophie Richon, Virginie Dangles-Marie, Eric Pasmant, Raphaël Margueron, Mikael Hivelin
Published: 202510.3791/68694
Abstract
Neurofibromatosis type 1 (NF1) is a genetic disorder caused by pathogenic variants in the NF1 gene, leading to the loss of neurofibromin function and the development of benign peripheral nerve sheath tumors known as neurofibromas. While genetically e…
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