Journal of visualized experiments : JoVEAnimalsMiceRetinal Pigment EpitheliumMacular DegenerationDisease Models
Alu RNA-transfected Primary Mouse Retinal Pigment Epithelium: A Pathologically Relevant In Vitro Model for Age-related Macular Degeneration.
Xinyue Hu, Yuhao Tang, Haoliang Zhang, Zilin Wang, Junran Sun
Published: 202510.3791/68570
Abstract
Age-related macular degeneration (AMD), particularly non-exudative AMD, requires experimental models that better replicate human pathology. Current in vivo models remain technically demanding and time-intensive, whereas conventional in vitro systems…
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