Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhiHumansMultiple MyelomaMetabolomics
[Progress in metabolomics of multiple myeloma].
X Ye, Z X Sun, X Y Qu, L Fan
Published: 202510.3760/cma.j.cn121090-20241205-00536
Abstract
Open AccessMultiple myeloma (MM) is a malignant disease characterized by clonal plasma cell proliferation, with metabolic reprogramming. Abnormal metabolism of amino acids, glucose, lipids and nucleotides plays a crucial role in various pathological processes in MM, such as proliferation, metastasis, immune escaping and drug resistance. This review summarized the application of metabolomics technology in identifying biomarkers for MM and targeting related metabolic pathways. The objective is to guide further investigations into the metabolic mechanisms underlying MM and encourage innovation in clinical diagnosis and treatment strategies for this disease.