Acta biochimica et biophysica Sinica
The DNA-PKcs-primary cilia axis maintains ionizing radiation-induced senescence in tumor cells.
Xiuzhu Liu, Li Wei, Rong Zhang, Jiaxin Chen, Tongshan Zhang, Junrui Hua, Jufang Wang, Jinpeng He, Xiaodong Xie
Published: 202510.3724/abbs.2025168
Abstract
Senescence is a cellular response closely associated with genotoxic stress and plays a critical role in determining cell fate following irradiation exposure. Primary cilia, which are sensory organelles on the cell surface, detect and transmit diverse…
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