Highlights in HIV 2022-2024.

This manuscript summarizes the most relevant publications and international conference presentations on HIV infection between 2022 and 2024. It provides updated epidemiological data on HIV in Spain and assesses healthcare professionals' knowledge regarding HIV transmission and prevention. It also discusses the REPRIEVE study, given its significant clinical implications for the management of people living with HIV. In addition, it reviews recent advances in antiretroviral therapy and pre-exposure prophylaxis, focusing on dual therapy regimens and long-acting injectable treatments, due to their significant clinical impact on the management of people living with HIV.