Kidney360
Lactulose, a Disaccharide Prebiotic, Improves the Gut-Kidney Axis via Enhancement of Akkermansia Muciniphila Production.
Miyu Sueyoshi, Hiroshi Watanabe, Moritaka Goto, Takao Sato, Mai Hashimoto, Mayu Oki, Ebenezer Ofori-Attah, Takehiro Nakano, Hitoshi Maeda, Motoko Tanaka, Kazutaka Matsushita, Hideaki Jinnouchi, Toru Maruyama, Daisuke Kadowaki
Published: 202510.34067/KID.0000001040
Abstract
BACKGROUND: Recently, we reported that lactulose, a synthetic disaccharide used to treat chronic constipation, improved the gut-renal axis in mice with adenine-induced CKD. However, the underlying mechanism remains unclear. Akkermansia muciniphila (A…
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