Veterinary sciences
Structural and Functional Analysis of Porcine CR1-like Proteins in C4b-Mediated Immune Responses.
Wei Yin, Nan Wang, Jingze Li, Haoxiang Yao, Qiongyu Li, Hongquan Li, Kuohai Fan, Jia Zhong, Zhenbiao Zhang, Na Sun, Panpan Sun, Huizhen Yang, Jianzhong Wang, Yaogui Sun
Published: 202510.3390/vetsci13010033
Abstract
The complement system is crucial for immune defense, linking innate and adaptive immunity. In the classical and lectin pathways, C4 is split into C4b, triggering opsonization, lysis, and the removal of pathogens and damaged cells. Dysregulated activa…
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