VirusesCD47 AntigenHumansSARS-CoV-23' Untranslated RegionsSpike Glycoprotein
The Introduction of a HuR-Binding Site in the 3' UTR and the CD47 Cytoplasmic Tail Enhances SARS-CoV-2 S-Protein Expression in Cells.
Ivan M Pereverzev, Irina A Bakhno, Kristina I Yakovleva, Ilya S Dovydenko, Evgeniya E Burkova
Published: 202610.3390/v18010137
Abstract
In this study, we constructed plasmids to increase the overall expression level of the SARS-CoV-2 S-protein and its presentation on the cell surface. To this end, we designed a series of plasmid constructs encoding the SARS-CoV-2 S-protein with modif…
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