ToxinsHumansIbuprofenMaleFemaleMiddle Aged
Optimization of Ibuprofen Route and Dosage to Enhance Protein-Bound Uremic Toxin Clearance During Hemodialysis.
Víctor Joaquín Escudero-Saiz, Elena Cuadrado-Payán, María Rodríguez-García, Gregori Casals, Lida María Rodas, Néstor Fontseré, María Del Carmen Salgado, Carla Bastida, Nayra Rico, José Jesús Broseta, Francisco Maduell
Published: 202610.3390/toxins18010037
Abstract
Protein-bound uremic toxins (PBUT), particularly indoxyl sulphate (IS) and p-cresyl sulphate (pCS), are poorly removed by conventional haemodialysis because of their strong albumin binding. These toxins are associated with cardiovascular morbidity an…
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