Pharmaceutics
Impeding the NHEJ Pathway for Overcoming Radioresistance in the Context of Precision Radiotherapy of Cancer.
Dragoș Andrei Niculae, Radu Marian Șerban, Dana Niculae, Doina Drăgănescu
Published: 202610.3390/pharmaceutics18010131
Abstract
Non-homologous end joining (NHEJ) is a critical DNA double-strand break (DSB) repair pathway that operates throughout the cell cycle to maintain the genomic stability of the cell. Unlike homologous recombination (HR), NHEJ is capable of repairing DSB…
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