Pharmaceutics
Construction and Characterization of PDA@MnO2-Cored Multifunctional Targeting Nanoparticles Loaded with Survivin siRNA for Breast Tumor Therapy.
Jing Zhang, Wenhao Jiang, Lei Hu, Qing Du, Nina Filipczak, Satya Siva Kishan Yalamarty, Xiang Li
Published: 202510.3390/pharmaceutics18010010
Abstract
Objective: This study aims to engineer a novel nanoparticle formulation for combined tumor therapy, designated as PDA@Mn-siSur-c-NPs, which comprises a polydopamine/manganese dioxide (PDA@MnO2) core alongside survivin-targeting siRNA and cyclo(RGD-DP…
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