Pharmaceuticals (Basel, Switzerland)
TAT-PBX1 Reverses Hyperglycemia Through β-Cell Regeneration and Functional Restoration in an STZ-Induced Diabetic Model.
Xiangyuan Meng, Zhenhu Zhao, Xin Zhang, Ruihan Guo, Shuran Yang, Shuhua Mao, Ziyu Zong, Jinyu Liu
Published: 202610.3390/ph19010085
Abstract
Objective: β-cell dysfunction and loss are major pathological determinants of impaired islet function and hyperglycemia in diabetes. Given the inability of current therapies to restore β-cell viability or glucose-responsive insulin secretion, this st…
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