Pharmaceuticals (Basel, Switzerland)
Unraveling Cannabidiol's Bidirectional Regulation of Melatonin Pharmacokinetics via PEPT1/CYP1A2: Mechanistic Insights and Quantitative Projections.
Bohong Zheng, Mengran Wang, Qiannan Zhang, Cong Li, Lingchao Wang, Wenpeng Zhang, Chunyan Liu, Xiaomei Zhuang
Published: 202510.3390/ph19010080
Abstract
Background: Chronic insomnia is associated with elevated cardiovascular disease risk, and current therapeutic options for this condition remain inadequate. Melatonin (MT) combined with cannabidiol (CBD) may exert synergistic effects on improving slee…
Preview only. Read the full abstract at the source