Pharmaceuticals (Basel, Switzerland)
Elucidation of a Novel Dual Binding Site on Tubulin: Theoretical Insights and Prospective Hybrid Inhibitors.
Dmytro Khylyuk, Oleg M Demchuk, Rafał Kurczab, Barbara Miroslaw, Monika Wujec
Published: 202510.3390/ph19010003
Abstract
Background/Objectives: Microtubule-targeting agents remain foundational components of anticancer chemotherapy, yet their clinical utility is constrained by resistance and toxicity. Methods: Here, we present a theoretical exploration of a plausible "d…
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