Pathogens (Basel, Switzerland)HumansViral Fusion ProteinsDrug DesignPeptidesAntiviral Agents
Structure-Guided Design of Peptide Inhibitors Targeting Class I Viral Fusion Proteins.
Narendra Kumar Gonepudi, Harry Baffour Awuah, Wang Xu, Revansiddha H Katte, Maolin Lu
Published: 202510.3390/pathogens15010032
Abstract
Viral fusion proteins are indispensable mediators of viral entry that orchestrate the fusion of viral and host membranes, making them primary targets for antiviral interventions. Class I fusion proteins, displayed on the surface of enveloped viruses…
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