Molecules (Basel, Switzerland)
Straightforward Synthetic Approach to Aminoalcohols with 9-oxabicyclo[3.3.1]nonane or Cyclooctane Core via Nucleophilic Ring-Opening of Spirocyclic Bis(oxiranes).
Olga V Ryzhikova, Daiana V Savchenkova, Sergey V Kositov, Yuri K Grishin, Olga A Maloshitskaya, Kseniya N Sedenkova, Elena B Averina
Published: 202610.3390/molecules31020252
Abstract
Nucleophilic ring-opening of bis(oxiranes), containing several reactive centers, can be used to elaborate straightforward atom-economy and stereoselective approaches to polyfunctionalized compounds. In the present work, ring-opening of cis- and trans…
Preview only. Read the full abstract at the source