Molecules (Basel, Switzerland)CanagliflozinSpectroscopyNear-InfraredTabletsLeast-Squares Analysis
Simultaneous Quantitative Analysis of Polymorphic Impurities in Canagliflozin Tablets Utilizing Near-Infrared Spectroscopy and Partial Least Squares Regression.
Mingdi Liu, Rui Fu, Guiyu Xu, Weibing Dong, Huizhi Qi, Peiran Dong, Ping Song
Published: 202610.3390/molecules31020230
Abstract
Canagliflozin (CFZ), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is extensively utilized in the management of type 2 diabetes. Among its various polymorphic forms, the hemi-hydrate (Hemi-CFZ) has been selected as the active pharmaceutical ing…
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