Micromachines
A Multifunctional Peptide Linker Stably Anchors to Silica Spicules and Enables MMP-Responsive Release of Diverse Bioactive Cargos.
So-Hyung Lee, Suk-Hyun Kwon, Byung-Ho Song, In-Gyeong Yeo, Hyun-Seok Park, A-Ri Kim, Lee-Seul Kim, Ji-Min Noh, Hee-Jung Choi, Da-Jeoung Lim, Young-Wook Jo
Published: 202610.3390/mi17010127
Abstract
Silica spicules provide a natural transdermal conduit but require a linker that binds strongly under physiological conditions and releases payloads selectively in response to biological cues. Existing silane chemistries or polydopamine coatings lack…
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