Metabolites
CAR Intrinsic Design Pre-Shapes Transcriptional and Metabolic Networks in CAR T Cells.
Didem Agac Cobanoglu, Samantha Franklin, Yue Hu, Devon J Boland, Xiaotong Song
Published: 202610.3390/metabo16010052
Abstract
BACKGROUND/OBJECTIVES: Chimeric antigen receptor (CAR) T cells are a powerful cancer therapy, but their function depends heavily on internal signaling domains and metabolic adaptability. Most studies evaluate CAR behavior upon antigen exposure, yet i…
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