Marine drugsAnimalsMetabolomicsConotoxinsTobacco Use DisorderNicotine
Hippocampal Metabolomics Reveal the Mechanism of α-Conotoxin [S9K]TxID Attenuating Nicotine Addiction.
Meiting Wang, Weifeng Xu, Huanbai Wang, Cheng Cui, Rongyan He, Xiaodan Li, Jinpeng Yu, J Michael McIntosh, Dongting Zhangsun, Sulan Luo
Published: 202610.3390/md24010043
Abstract
Nicotine is the main substance responsible for the development of tobacco addiction. The α3β4 nicotinic acetylcholine receptors (nAChRs) are a potential key target for mitigating nicotine reward. Preliminary studies in our laboratory suggest that α-c…
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