Journal of clinical medicine
Hepatotoxicity Risk of Isoniazid in Patients with Autoimmune Rheumatic Diseases and Prior Liver Injury Due to Disease-Modifying Antirheumatic Drugs: A Single-Center Experience and Literature Review.
Joy Selene Osorio-Chávez, Virginia Portilla González, Iván Ferraz-Amaro, Santos Castañeda, José Manuel Cifrián Martínez, Ricardo Blanco Alonso
Published: 202610.3390/jcm15020432
Abstract
Background/Objectives: Patients with rheumatic immune-mediated inflammatory diseases (R-IMID) require latent tuberculosis infection screening and, in case of positivity, chemoprophylaxis. Isoniazid INH remains the standard regimen, but hepatotoxicity…
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