International journal of molecular sciencesHumansGraves DiseaseEpigenesisGeneticGraves Ophthalmopathy
Beyond the Genome: Can Epigenetics Forecast Therapeutic Success in Graves' Disease and Thyroid Eye Disease?
Jacopo Manso, Dario Sardone, Vincenzo Marotta, Antonio Stefano Salcuni, Alessandro Brunetti, Claudia Cipri, Silvia Maria Sciannimanico, Lorenzo Piva, Maria Carpentieri, Alberto Falchetti, Fabio Vescini
Published: 202610.3390/ijms27021116
Abstract
Graves' disease (GD) and Thyroid Eye Disease (TED) are autoimmune disorders characterized by significant heterogeneity in treatment response. Up to 50% of GD patients relapse after antithyroid drug (ATD) withdrawal, and a substantial portion of TED p…
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