International journal of molecular sciencesHumansMatrix Metalloproteinase 9FemaleMalePolymorphism
Association of MMP9 and NOS3 Polymorphisms with Distinct Clinical Forms of Juvenile Scleroderma and Characteristics of Humoral Immunity.
Maria Osminina, Vera Podzolkova, Maria Litvinova, Natalia Geppe, Svetlana Chebysheva, Lusine Khachatryan, Natalia Golovanova, Yulia Kostina, Oksana Lazareva-Batyreva, Angelina Polyanskaya, Olga Shpitonkova, Tatiana Subbotina, Tigran Areian, Nadezhda Podchernyaeva
Published: 202610.3390/ijms27021109
Abstract
Juvenile scleroderma (JS), comprising localized (JLSd) and systemic (JSSc) forms, is a rare autoimmune disorder. This study investigated associations of polymorphisms in extracellular matrix (MMP1, MMP9) and vascular homeostasis (NOS3) genes with JS…
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