International journal of molecular sciencesAnimalsRatsInbred SHRArteriolesHypertension
Effects of N3SA Analogues on Cerebral and Peripheral Arteriolar Vasomotion in Spontaneously Hypertensive Rats.
Dominga Lapi, Giuseppe Federighi, Maria Paola Tramonti Fantozzi, Gianpiero Garau, Rossana Scuri
Published: 202610.3390/ijms27021006
Abstract
Thiazides are among the most efficacious and commonly used drugs for the treatment of hypertension. The nanomolar stabilizer N3SA binds specifically to the recently discovered thiazide-binding site of the membrane target NAPE-PLD, showing sustained a…
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