International journal of molecular sciencesDendritic CellsHumansHIV-1HIV InfectionsTranscriptome
Transcriptomic Signatures of Immune Suppression and Cellular Dysfunction Distinguish Latent from Transcriptionally Active HIV-1 Infection in Dendritic Cells.
Shirley Man, Jade Jansen, Neeltje A Kootstra, Teunis B H Geijtenbeek
Published: 202610.3390/ijms27020844
Abstract
Dendritic cells (DCs) are essential for antiviral immunity but are also susceptible to HIV-1 infection. Although sensing and restriction pathways in DCs are well described, the mechanisms underlying latent infection and its functional consequences re…
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