International journal of molecular sciencesAnimalsAnti-Bacterial Agentsbeta-LactamsSerum AlbuminProtein Binding
Structural Interactions of β-Lactam Antibiotics with Mammalian Serum Albumins.
Kajetan Duszynski, Bartosz Sekula, Julita Talaj, Anna Bujacz
Published: 202610.3390/ijms27020776
Abstract
The Bactericidal action of β-lactam antibiotics is related to covalent modification of transpeptidases, enzymes that take part in the synthesis of bacterial cell wall. The β-lactam moiety mimics the transpeptidase substrate and irreversibly inhibits…
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