International journal of molecular sciencesAnimalsCyclophosphamideMyeloid-Derived Suppressor CellsMiceImmunomodulation
Cyclophosphamide-Mediated Induction of Myeloid-Derived Suppressor Cells In Vivo: Kinetics of Accumulation, Immune Profile, and Immunomodulation by Oleanane-Type Triterpenoids.
Mona S Awad, Aleksandra V Sen'kova, Andrey V Markov, Oksana V Salomatina, Marina A Zenkova, Oleg V Markov
Published: 202610.3390/ijms27020564
Abstract
Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that strongly suppress immunity and expand during tumor progression. Various antitumor chemotherapy agents can induce MDSC accumulation, reducing treatment effectiveness. We investig…
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