Faster than Virus: The Physics of Pandemic Prediction.
Serena Vita, Giovanni Morlino, Alessandra D'Abramo, Laura Scorzolini, Gaetano Maffongelli, Delia Goletti, Francesco Vairo, Enrico Girardi, Massimo Ciccozzi, Emanuele Nicastri
Abstract
Open AccessBACKGROUND: Zoonotic spillover events with pandemic potential are increasingly associated with environmental change, ecosystem disruption, and intensified human-animal interactions. Although the specific origin and timing of future pandemics remain uncertain, there is a clear need to complement traditional preparedness strategies with approaches that support earlier anticipation and prevention. OBJECTIVES: This study aims to propose a conceptual approach to reframe pandemic preparedness toward proactive surveillance and spillover prevention. METHODS: We introduce a tachyon-inspired conceptual approach, using a thought experiment based on hypothetical faster-than-light particles to illustrate anticipatory observation of pandemic emergence. The framework is informed by interdisciplinary literature on emerging infectious diseases, One Health surveillance, predictive epidemiology, and public-health preparedness. RESULTS: The proposed approach highlights the importance of proactive, integrated surveillance systems that combine human, animal, and environmental data. Key elements include the use of advanced analytical tools such as neural networks, early characterization of population risk profiles, strengthened public-health infrastructure, coordinated governance, adaptable financial resources, and a resilient healthcare workforce. The integration of animal welfare considerations, translational research, and planetary health principles is emphasized as central to reducing spillover risk. CONCLUSIONS: Tachyon-inspired thinking offers a conceptual tool to support a shift from reactive pandemic response toward proactive anticipation and prevention. Embedding integrated surveillance and One Health principles into public-health systems may enhance early detection capacity and contribute to mitigating the impact of future pandemics.