GenesAnimalsGenetic VectorsMiceReceptorsLDL
Efficiency of Lentiviral Vectors Pseudotyped with LCMV-G in Gene Transfer to Ldlr-/-ApoB100/100 Mice.
Alisa Nousiainen, Anna-Kaisa Ruotsalainen, Krista Hokkanen, Svetlana Laidinen, Ahmed Tawfek, Diana Schenkwein, Seppo Ylä-Herttuala
Published: 202610.3390/genes17010060
Abstract
Background/Objectives: Lentiviral vectors (LVs) are most commonly pseudotyped with the vesicular stomatitis virus glycoprotein (VSV-G), which lends LVs a wide tropism as it uses the low-density lipoprotein receptor (LDLR) as the main receptor for cel…
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