Current oncology (Toronto, Ont.)HumansGlioblastomaTumor Suppressor Protein p53Brain NeoplasmsClass I Phosphatidylinositol 3-Kinases
Family and Physician Perspectives: Unassailable, a p53 and PIK3CA Mutant Glioblastoma in a Child.
Mary-Pat Schlosser, Lea Stelter, Mike Stelter
Published: 202510.3390/curroncol33010008
Abstract
High-grade gliomas in children continue to have a dismal prognosis. This case is of a child with a diffuse pediatric-type high-grade glioma H3 and IDH-wildtype, treated with surgery, radiation, chemotherapy, and a targeted agent without success. Phys…
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