CellsAnimalsMiceGlycosylationMyoblastsCell Line
Gne-Depletion in C2C12 Myoblasts Leads to Alterations in Glycosylation and Myopathogene Expression.
Carolin T Neu, Aristotelis Antonopoulos, Anne Dell, Stuart M Haslam, Rüdiger Horstkorte
Published: 202610.3390/cells15020199
Abstract
GNE myopathy is a rare genetic neuromuscular disorder caused by mutations in the GNE gene. The respective gene product, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), is a bifunctional enzyme that initiates endogenous sialic ac…
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