CellsAnimalsMicrogliaPlaqueAmyloidCerebellum
Cerebellar Resistance to Amyloid Plaque Deposition and Elevated Microglial ECM Proteoglycan Uptake in 5xFAD Mice.
Carla Cangalaya, Henning Peter Düsedau, Ildiko Rita Dunay, Alexander Dityatev, Stoyan Stoyanov
Published: 202610.3390/cells15020182
Abstract
In both Alzheimer's disease (AD) patients and animal models, senile plaques are generally observed in the cerebral cortex rather than the cerebellum. The mechanisms underlying the regional resistance of the cerebellum to amyloid plaque deposition rem…
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