BiomoleculesInterleukin-8Chondroitin SulfatesHumansProtein BindingMolecular Dynamics Simulation
Structural Basis of Chemokine CXCL8 Monomer and Dimer Binding to Chondroitin Sulfate: Insights into Specificity and Plasticity.
Bryon P Mahler, Balaji Nagarajan, Nehru Viji Sankaranarayanan, Prem Raj B Joseph, Umesh R Desai, Krishna Rajarathnam
Published: 202610.3390/biom16010124
Abstract
Chemokines play a central role in orchestrating neutrophil recruitment from the bloodstream and determining their effector functions at sites of infection. Chemokine activity is determined by three key properties: reversible monomer-dimer equilibrium…
Preview only. Read the full abstract at the source