BiomoleculesMaleHumansFerroptosisProstatic NeoplasmsDiosgenin
Methyl Protodioscin Promotes Ferroptosis of Prostate Cancer Cells by Facilitating Dissociation of RB1CC1 from the Detergent-Resistant Membranes and Its Nuclear Translocation.
Ruonan Wang, Chaoyu Hu, Yi Zhao, Shuhan Wu, Shujuan Cao, Leiming Xu, Dengke Yin, Song Tan
Published: 202510.3390/biom16010038
Abstract
Methyl protodioscin (MPD), a furostanol saponin found in the rhizomes of Dioscorea plants, has been shown to effectively inhibit proliferation of prostate cancer cells in vitro and in vivo. However, the mechanism underlying this inhibitory action rem…
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